An (incomplete) list of Games with enhancements/changes in the Macintosh version over the original DOS version:

* Leisure Suit Larry 1 - The Land of the Lounge Lizards (Sierra, 1987)
- 2 graphic sets for 2-bit (bw) and 4-bit (16 color) screens
- uses an icon-based interface menu
- uses text windows with enhanced font instead of pure text

* Gold Rush! (Sierra, 1989)
- 2 graphic sets for 2-bit (bw) and 4-bit (16 color) screens
- uses an icon-based interface menu
- uses text windows with enhanced font instead of pure text

* Space Quest 3: The Pirates of Pestulon (Sierra, 1989)
- 2 graphic sets for 2-bit (bw) and 4-bit (16 color) screens
- Finder interface

* Leisure Suit Larry 5 (Sierra, 1991)
- additional sounds (sound samples: toilet flush, airport announcement, …)
(is explicitly mentioned in the credits, with the possibility to replay the sound samples using a soundboard-like interface)

* Indiana Jones and the Last Crusade (LucasFilm Games, 1990)
- 2 graphic sets for 2-bit (bw) and 4-bit (16 color) screens
- uses an icon-based interface instead of a text-based interface

* Loom (LucasFilm Games, 1990)
- 2 graphic sets for 2-bit (bw) and 4-bit (16 color) screens
- uses same engine as "Indiana Jones and the Last Crusade" but without the icon-based interface

* The Secret of Monkey Island (LucasFilm Games, 1990)
- VGA graphics only
- higher screen solution (640x480) possible (3 sizes possible in total: low, medium, high)
- graphics smoothed by filter
- uses an advanced, MI2-like graphical interface instead of a text-based interface

* Monkey Island 2: LeChuck's Revenge (LucasArts, 1991)
- higher screen solution (640x480) possible (3 sizes possible in total: low, medium, high)
- graphics smoothed by filter (can be disabled as an easter egg by entering the word "rough")

* Indiana Jones and the Fate of Atlantis (LucasArts, 1992)
- higher screen solution (640x480) possible (3 sizes possible in total: low, medium, high)
- graphics smoothed by filter (can be disabled as an easter egg by entering the word "rough")

* Civilization (Microprose, 1993)
- 2 graphic sets for 2-bit (bw) and 8-bit (256 color) screens
- Finder-based Interface with resizable window for the playfield
- enhanced sounds (sound samples)
- is identical with the Windows 3.x version

* Railroad Tycoon (Microprose, 1991)
- 2 graphic sets for 2-bit (bw) and 8-bit (256 color) screens
- Finder-based Interface with resizable window for the playfield
- enhanced sounds (sound samples)
- some screens (title, credits, main screen, broker screen, train screen) are redrawn in a vintage-looking brown style
- 2 animated screens (bridge building, train crash) missing

* Wolfenstein 3D (id Software, 1994)
- higher screen solution (640x480) possible
- enhanced graphics (redrawn textures and sprites)
- also playable by mouse
- two more weapons (flamethrower, rocket launcher)
- automap feature
- gameplay differences as of the Atari Jaguar version

* Command & Conquer (Westwood, 1995)
- higher screen solution (640x480) possible
- is identical with the Windows 95 version (Command & Conquer Gold)

Please feel comfortable to complete the list.

SimCity 2000 by Maxis offers near-unlimited resolution (the screen size is the limit--DOS users are stuck with their original resolution). Tons of other games have much higher resolution.

In short, when compared to their DOS counterparts, the Mac versions are usually better in graphics and sound--QuickTime is often used in Mac games, which uses MT-32 SFX (licensed by Roland). The SoundBlaster, on contrast, is a lousy, wheezy POS.

But DOS games are way easier to run on modern systems (ironically) including modern Macs. Basilisk or SheepShaver won't run them quite right...if at all (plus, they're very clunky to work with)

One game that didn't improve? King's Quest VI. Unfortunately, although Macs got the floppy disk version, they never got the CD-ROM enhanced version that came afterwards with improved graphics and sound.